Immune Response Role of Angiogenesis Inhibitors
نویسندگان
چکیده
منابع مشابه
Role of angiogenesis inhibitors in cancer treatment.
Angiogenesis is essential for the growth of both primary and metastatic tumors. This process, more complex than was previously thought, requires the coordinated activities of multiple factors and cell types. For tumors to develop a neovascular blood supply, tumor and host cells must secrete pro-angiogenic factors that offset the activities of inhibitory angiogenic factors. In addition, the newl...
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Angiogenesis, the formation of new blood vessels, is required for many pathologic processes, including invasive tumor growth as well as physiologic organ/tissue maintenance. Angiogenesis during development and adulthood is likely regulated by a balance between endogenous proangiogenic and antiangiogenic factors. It is speculated that tumor growth requires disruption of such balance; thus, the a...
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In the course of embryonic development, during some normal physiological processes in the adult, such as the female reproductive cycle, and also in a variety of pathologies, including tumour growth, new blood vessels develop from the pre-existing vascular network through endothelial cell sprouting, proliferation and fusion a process termed angiogenesis (Risau, 1997). Blocking tumour angiogenesi...
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Chemotaxis refers to the unidirectional movement of a cell in response to a chemical gradient. Leucocytes move from a low to a high concentration of chemoattractant. In the absence of a gradient, chemotactic factors increase the random motion of leucocytes. This has been termed chemokinesis. The directed migration, or chemotaxis, of immune cells is an essential feature of the immune system. It ...
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ژورنال
عنوان ژورنال: Clinical Oncology and Research
سال: 2021
ISSN: 2613-4942,2613-4942
DOI: 10.31487/j.cor.2021.02.01